Professor, Highly Cited Global Scientists of Thomson Reuters


Professor, Highly Cited Global Scientists of Thomson Reuters

Email: zouquan(a)

Office phone:


2000-2004   Harbin Institute of Technology   B.D

2004-2009   Harbin Institute of Technology   Ph.D

Work Experience

2009-2015       Xiamen University                                                        Associate Professor

2015-2018       Tianjin University                                                          Professor

2018-Present   University of Electronic Science and Technology        Professor

Research Interests


Selected Publications

  1. Xiangxiang Zeng, Wei Lin, Maozu Guo, Quan Zou*. A comprehensive overview and evaluation of circular RNA detection tools. PLoS Computational Biology. 2017,13(6): e1005420 (SCI, IF2015=4.587, PMID: 28594838) (data and codes)

  2. Quan Zou*, Qinghua Hu, Maozu Guo, Guohua Wang*. HAlign: Fast Multiple Similar DNA/RNA Sequence Alignment Based on the Centre Star Strategy. Bioinformatics. 2015,31(15): 2475-2481. (SCI, IF2016=7.307, PMID: 25812743) (Software)(该软件被OMICTOOLS推荐)

  3. Wei Tang, Shixiang Wan, Zhen Yang, Andrew E. Teschendorff*, Quan Zou*. Tumor Origin Detection with Tissue-Specific miRNA and DNA methylation Markers. Bioinformatics. 2018, 34(3): 398-406. (SCI, IF2016=7.307, PMID:29028927) (web server)

  4. Leyi Wei, Shasha Luan, Luis Eijy Nagai, Ran Su*, Quan Zou*. Exploring sequence-based features for the improved prediction of DNA N4-methylcytosine sites in multiple species. Bioinformatics. Doi: 10.1093/bioinformatics/bty824. (web server)

  5. Cangzhi Jia*, Yun Zuo, Quan Zou*. O-GlcNAcPRED-II: an integrated classification algorithm for identifying O-GlcNAcylation sites based on fuzzy undersampling and a K-means PCA oversampling technique. Bioinformatics. 2018, 34(12): 2029-2036. (SCI, IF2016=7.307, PMID:29420699)(web server)(该软件被OMICTOOLS推荐)

  6. Xiangxiang Zeng, Li Liu, Linyuan Lu*, Quan Zou*. Prediction of potential disease-associated microRNAs using structural perturbation method. Bioinformatics. 2018, 34(14): 2425-2432.(SCI, IF2016=7.307, PMID:29490018)(codes)

  7. Wenying He, Cangzhi Jia*, Quan Zou*. 4mCPred: Machine Learning Methods for DNA N4-methylcytosine sites Prediction. Bioinformatics. doi: 10.1093/bioinformatics/bty668 (SCI, IF2016=7.307, PMID: 30052767)(web server)

  8. Jianbo Pan, Shichang Hu, Hao Wang, Quan Zou*, Zhiliang Ji*. PaGeFinder: Quantitative Identification of Spatiotemporal Pattern Genes. Bioinformatics. 2012, 28(11):1544-1545. (SCI, IF2016=7.307, PMID:22492640)(Web Server)

  9. Quan Zou, Gang Lin, Xingpeng Jiang, Xiangrong Liu, Xiangxiang Zeng. Sequence clustering in bioinformatics: an empirical study. Briefings in Bioinformatics. Doi: 10.1093/bib/bby090 (data)

  10. Quan Zou*, Xubin Li, Wenrui Jiang, Ziyu Lin, Guilin Li, Ke Chen. Survey of MapReduce Frame Operation in Bioinformatics. Briefings in Bioinformatics. 2014,15(4): 637-647. (SCI, IF2015=8.399, PMID: 23396756)

  11. Xiangxiang Zeng, Xuan Zhang, Quan Zou*. Integrative approaches for predicting microRNA function and prioritizing disease-related microRNA using biological interaction networks. Briefings in Bioinformatics. 2016,17(2):193-203.(SCI, IF2015=8.399,PMID:26059461)

  12. Wenhe Su, Xiangke Liao, Yutong Lu, Quan Zou*, Shaoliang Peng*. Multiple Sequence Alignment Based on a Suffix Tree and Center-Star Strategy: A Linear Method for Multiple Nucleotide Sequence Alignment on Spark Parallel Framework. Journal of Computational Biology. 2017, 24(12): 1230-1242 (SCI, IF2016=1.032, PMID: 29116822) (codes)(该软件被OMICTOOLS推荐)

  13. Pei Li, Maozu Guo, Chunyu Wang, Xiaoyan Liu, Quan Zou*. An overview of SNP interactions in genome-wide association studies. Briefings in Functional Genomics. 2015, 14(2):143-155. (SCI, IF2015=3.124,PMID: 25241224)

  14. Quan Zou, Jinjin Li, Li Song, Xiangxiang Zeng, Guohua Wang. Similarity computation strategies in the microRNA-disease network: A Survey. Briefings in Functional Genomics. 2016, 15(1): 55-64. (SCI, IF2015=3.124,PMID: 26134276)

  15. Leyi Wei, Pengwei Xing, Gaotao Shi, Zhiliang Ji*, Quan Zou*. Fast prediction of protein methylation sites using a sequence-based feature selection technique. IEEE/ACM Transactions on Computational Biology and Bioinformatics. Doi: 10.1109/TCBB.2017.2670558. (SCI, IF2015=1.609, PMID:28222000)(web server)(该软件被OMICTOOLS推荐)

  16. Xiangxiang Zeng, Yuanlu Liao, Yuansheng Liu, Quan Zou*. Prediction and validation of disease genes using HeteSim Scores. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2017, 14(3):687-695. (SCI, IF2015=1.609, PMID:26890920)(Codes and Data)

  17. Yuansheng Liu, Xiangxiang Zeng, Zengyou He*, Quan Zou*. Inferring microRNA-disease associations by random walk on a heterogeneous network with multiple data sources. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2017, 14(4): 905-915.(Web Server)(SCI, IF2015=1.609, PMID:27076459)

  18. Leyi Wei, Minghong Liao, Yue Gao, Rongrong Ji, Zengyou He*, Quan Zou*. Improved and Promising Identification of Human MicroRNAs by Incorporating a High-quality Negative Set. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2014, 11(1):192-201 (Software) (SCI, IF2015=1.609, PMID: 24216114)

  19. Leyi Wei, Pengwei Xing, Jijun Tang, Quan Zou*. PhosPred-RF: a novel sequence-based predictor for phosphorylation sites using sequential information only. IEEE Transactions on NanoBioscience. 2017, 16(4): 240-247. (SCI, IF2015=1.969, PMID:28166503) (web server)

  20. Leyi Wei, Jijun Tang, Quan Zou*. Local-DPP: An Improved DNA-binding Protein Prediction Method by Exploring Local Evolutionary Information. Information Sciences. 2017, 384:135-144. (SCI, IF2015=3.364)(web server)

  21. Leyi Wei, Yijie Ding, Ran Su, Jijun Tang, Quan Zou*. Prediction of human protein subcellular localization using deep learning. Journal of Parallel and Distributed Computing. 2018, 117: 212-217 (SCI, IF2015=1.320)

  22. Shixiang Wan, Yucong Duan, Quan Zou*. HPSLPred: An Ensemble Multi-label Classifier for Human Protein Subcellular Location Prediction with Imbalanced Source. Proteomics. 2017, 17: 1700262. (SCI, IF2015=4.079, PMID: 28776938) (web server)(该软件被OMICTOOLS推荐)

  23. Leyi Wei, Pengwei Xing, Ran Su, Gaotao Shi, Zhanshan Sam Ma*, Quan Zou*. CPPred-RF: a sequence-based predictor for identifying cell-penetrating peptides and their uptake efficiency. Journal of Proteome Research. 2017, 16(5):2044-2053.(SCI, IF2015=4.173, PMID: 28436664)(web server)

  24. Li Song, Dapeng Li, Xiangxiang Zeng, Yunfeng Wu, Li Guo*, Quan Zou*. nDNA-prot: Identification of DNA-binding Proteins Based on Unbalanced Classification. BMC Bioinformatics. 2014, 15:298. (SCI, IF2015=2.435, PMID: 25196432)(Web Server)

  25. Quan Zou, Shixiang Wan, Ying Ju, Jijun Tang, Xiangxiang Zeng. Pretata: predicting TATA binding proteins with novel features and dimensionality reduction strategy. BMC Systems Biology. 2016, 10(Suppl 4): 114(SCI, IF2015=2.208, PMID: 28155714)(Web Server)

  26. Wenying He, Cangzhi Jia, Yucong Duan, Quan Zou*. 70ProPred: a predictor for discovering sigma70 promoters based on combining multiple features. BMC Systems Biology. 2018,12(Suppl 4): 44(SCI, IF2015=2.208, PMID: 29745856)(Web Server)

  27. Quan Zou, Shixiang Wan, Xiangxiang Zeng, Zhanshan Sam Ma. Reconstructing evolutionary trees in parallel for massive sequences. BMC Systems Biology. 2017, 11(Suppl 6): 100 (web server)(SCI, IF2016=2.303, PMID: 29297337)(新浪科技报导)(搜狐报导)

  28. Leyi Wei, Jijun Tang, Quan Zou*. SkipCPP-Pred: An Improved and Promising Sequence-based Predictor for Predicting Cell-Penetrating Peptides. BMC Genomics. 2017, 18 (Suppl 7): 742 (SCI, IF2016=3.729, PMID: 29513192)(web server)(该软件被OMICTOOLS推荐)

  29. Xiangxiang Zeng, Ningxiang Ding, Alfonso Rodriguez-Paton, Quan Zou*. Probability-based collaborative filtering model for predicting gene-disease associations. BMC Medical Genomics. 2017,10(Suppl 5):76 (SCI, IF2016=2.848, PMID:29297351)

  30. Jing Jiang, Fei Xing, Xiangxiang Zeng, Quan Zou*. RicyerDB: A Database For Collecting Rice Yield-related Genes with Biological Analysis. International Journal of Biological Sciences. 2018, 14(8):965-970(SCI, IF2016=3.873, PMID:29989091). (web site)

  31. Shixiang Wan, Quan Zou*. HAlign-II: efficient ultra-large multiple sequence alignment and phylogenetic tree reconstruction with distributed and parallel computing. Algorithms for Molecular Biology. 2017,12: 25 (SCI, IF2015=1.439, PMID: 29026435 ) (Software)

  32. Wei Tang, Zhijun Liao, Quan Zou*. Which statistical significance test best detects oncomiRNAs in cancer tissues? An exploratory analysis. Oncotarget. 2016, 7(51):85613-85623.(SCI, IF2015=5.008, PMID: 27784000)(data and codes)

  33. Li Guo*, Jiafeng Yu, Tingming Liang, Quan Zou*. miR-isomiRExp: a web-server for the analysis of expression of miRNA at the miRNA/isomiR levels. Scientific Reports. 2016, 6: 23700. (SCI, IF2015=5.578, PMID: 27009551)(Web Server)

  34. Wei Chen, Pengwei Xing, Quan Zou*. Detecting N6-methyladenosine sites from RNA transcriptomes using ensemble Support Vector Machines. Scientific Reports. 2017, 7: 40242.(SCI, IF2015=5.578, PMID: 28079126) (Web Server)

  35. Quan Zou*, Yaozong Mao, Lingling Hu, Yunfeng Wu, Zhiliang Ji*. miRClassify: An advanced web server for miRNA family classification and annotation. Computers in Biology and Medicine. 2014, 45:157-160.(SCI, IF2015=1.521, PMID: 24480175) (Web Server) most cited articles in this journal